

Treatment with alpha-1 noradrenergic blockers (terazosin, doxazosin, tamsulosin, alfuzosin, or prazosin) or other prohibited medications.Use of benzodiazepines or other hypnotics or oral or short-acting intramuscular antipsychotic drugs in the 4 hours before study treatment.Patients with agitation caused by acute intoxication, including positive identification of alcohol by breathalyzer or drugs of abuse (with the exception of THC) during urine screening.Participants who agree to use a medically acceptable and effective birth control method.Patients who are in good general health prior to study participation as determined by a detailed medical history, physical examination, 12-lead ECG with rhythm strip, blood chemistry profile, hematology, urinalysis, and in the opinion of the Principal Investigator.Patients who read, understand and provide written informed consent.Patients who have a score of ≥ 4 on at least 1 of the 5 items on the PEC at Baseline.Patients who are judged to be clinically agitated at Screening and Baseline with a total score of ≥ 14 on the 5 items (poor impulse control, tension, hostility, uncooperativeness, and excitement) comprising the PANSS Excited Component (PEC).Patients who have met DSM-5 criteria for bipolar I or II disorder.Male and female patients between the ages of 18 to 75 years, inclusive.Why Should I Register and Submit Results?.That man has had his heart broken over this franchise so many times… the last interview I saw with him was really heart wrenching, he was so crushed by the failure of the movie… I’m not sure he’ll go back to it. The only question (and the most important one) is if Joss Whedon would agree to do another one.

Mark me down as being impressed if the studio actually decides to go ahead and fund something like this.

Nathan Fillion, says Tudyk, is especially keen.
SERENITY 2 MOVIE
“Everybody in the Firefly crew – and that includes the ones who died in the movie – are excited about the prospect of doing another”. Especially since the whole DVD sequel is a big trend. Tudyk agrees that even if it was a direct-to-DVD movie, it’d still be worthwhile. And now… there’s now a chance there’s going to be another movie”. “They had to put out because they’ve been selling out of the other one and so Universal’s like ‘So, let’s do another one’. Tudyk says the newly-released “Serenity : Special Edition“ DVD has been selling so hot, that there’s talk in doing another movie. This pretty much sealed the fate of the Serenity/Firefly franchise and it has been understood that there would be no sequel.īut wait a second! Strong sales of the Serenity special DVD have some folks at the studio thinking that a Serenity 2 might be a good idea! The folks at Moviehole give us this: when they DO put out something as brilliant as Serentiy, they don’t go support it). Sadly the show was pulled after only 12 episodes, but later appeared as ONE OF THE BEST SCI FI MOVIES IN THE LAST 10 YEARS! Serenity.įor various reasons, Serenity woefully BOMBED at the boxoffice (this is one of the big reasons I laugh when people complain that Hollywood doesn’t do anything original anymore…. It was cleaver, funny, exciting… everything you could want in a Sci Fi show along with some terrific characters. Firefly was a show unappreciated by the stupid network it was on.
